The day at a glance · 3 min read
Mood · Cautious
+25
Sentiment, −100 to +100
One Mind Festival Raised
$3.6M
Big Pharma & Biotech
DXCM 90-Day Return
27.79%+27.79%
MedTech & Devices
DXCM YTD Return
31.85%+31.85%
MedTech & Devices
Key driverPositive Phase 3 trial results for Amgen's dazodalibep in systemic Sjögren's disease drove biotech optimism, while FDA advisory support for Grail's multicancer blood test boosted diagnostics sentiment
Daily briefHealthcare· Money365.Market AI ·

Amgen Surges on Phase 3 Win; Grail Test Edges Toward FDA Nod

Dazodalibep data lifts Amgen 3.29%; FDA advisors back Grail multicancer screening; DexCom names new COO amid leadership overhaul

Big Pharma & Biotech

Bullish
AMGNBMYABBVLLY
Amgen (AMGN) reported positive topline Phase 3 OASIZ 301 results for dazodalibep in adults with moderate-to-severe systemic Sjögren's disease, showing statistically significant and clinically meaningful ESSDAI improvements sustained through Week 48 with generally mild to moderate side effects. The potential first-in-class CD40L antagonist could address an important unmet treatment need, as there are currently no approved disease-modifying therapies for persistent systemic Sjögren's. Shares rose following the announcement.
Bristol Myers Squibb (BMY) was added to the Zacks Rank #1 Strong Buy list, appearing on both strong buy and income stock rankings. The company participated as a presenting sponsor at the One Mind Music Festival, which raised over $3.6M to advance mental health research and discovery.
AbbVie (ABBV) announced a multi-year research collaboration with AI drug discovery startup Iambic Therapeutics, which filed for a U.S. IPO after raising money from NVIDIA and Qatar Investment Authority. Iambic will use its AI platform to discover and advance compounds for AbbVie under the partnership.
Eli Lilly (LLY) entered into a strategic research collaboration and license agreement with InnoCare Pharma to develop new medicines. InnoCare will leverage its proprietary drug discovery platform and extensive research experience to discover and advance compounds under the collaboration.

MedTech & Devices

Neutral
ISRGDXCM
Intuitive Surgical (ISRG) shares have declined 29% this year, though Wall Street analysts believe the robotic surgical systems leader's sell-off is overdone. The company remains a leader in surgical robotics despite the recent stock price weakness.
DexCom (DXCM) promoted former Chief Financial Officer Jereme Sylvain to EVP and Chief Operating Officer, with his new role now including responsibility for global operations and quality. Healthcare executive Glenn S. Boehnlein has joined DexCom's board of directors, adding external industry experience to governance. The leadership shift arrives as the company posts a 90-day share price return of 27.79% and year-to-date gain of 31.85%, though the 1-year total shareholder return of 29.97% contrasts with weaker longer-term performance.

FDA & Regulation

Bullish

Grail Stock (Week)

+35%+35%
ABT
FDA advisors recommended approval for the Grail multicancer blood test, with the stock rising 35% this week as the Food and Drug Administration considers the company's cancer blood test application. The advisory panel's positive recommendation marks a significant step toward potential approval of the screening technology.

Life Sciences Tools & Diagnostics

Bullish

Oxidative Stress Assay Market 2035

$2.7B

Reusable Bioreactors Market 2035

$24.7B

Cell Culture Media Market 2025

$3.9B

Cell Culture Media Market 2035

$10.8B
TMO
Thermo Fisher Scientific (TMO) was featured in multiple market outlook reports covering the life sciences tools sector through 2035. The global oxidative stress assay market is projected to reach $2.7 billion by 2035, driven by chronic disease research, personalized medicine, and automated high-throughput kits. The global reusable bioreactors market is expected to reach $24.7 billion by 2035 as biologics manufacturing expands, with demand driven by biologics, personalized therapies, and vaccine production. The global cell culture media market was valued at $3.9 billion in 2025 and is projected to reach $10.8 billion by 2035, driven by serum-free formulations, biologics, and cell therapies.

Looking Ahead

Neutral

MRK Close

$148.08-1.88%
AMGNMRNAPFEMRK
The UPLIZNA sales forecast and market analysis report projects growth through 2034, driven by new indications, global expansion, strong efficacy, differentiated CD19 targeting, and twice-yearly dosing, though competition is intensifying.
Moderna (MRNA) rallied to a fresh 52-week high amid positive company catalysts and improving investor sentiment.
Pfizer (PFE) scores 9/10 on technical and setup quality ratings, signaling strong trend momentum with a tight breakout setup.
Merck (MRK) closed at $148.08, marking a decline of 1.88% from the previous session.

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