The Week in Brief
- Nasdaq-100 rose 2.7% to close at $741.10; S&P 500 gained 0.72% while Dow and Russell 2000 declined
- Technology sector led with 2.7% gain; utilities fell 4.2% and energy dropped 2.7%
- Decliners outnumbered advancers 1,188 to 758; median stock fell 1.03%
- Meta Platforms Inc rose 16.8% and Intel Corp gained 17.3% among large-caps
- Moderna Inc added 26.5% after views on global pharma industry; Cullinan Therapeutics fell 26.8%
The S&P 500 rose 0.72% to close at $767.18 in a shortened four-trading-day week, while the Nasdaq-100 gained 2.72% to $741.10, outperforming on technology strength. The Dow Jones fell 0.62% to $512.68 and the Russell 2000 declined 0.86% to $281.66. Breadth was negative across the screened universe, with 1,188 decliners and 758 advancers among the 1,951 stocks analyzed; the median stock fell 1.03%.
Treasuries, gold, and oil all declined. The 20-plus year Treasury ETF fell 2.25% to $79.42, gold dropped 2.36% to $391.69, and crude oil edged down 0.47% to $153.09.
Index & Asset Scoreboard
Weekly price change of the major index and asset-class ETFs, Friday close to Friday close.
| Instrument | Sep 24 close | Week |
|---|---|---|
| S&P 500 (SPY) | $767.18 | ▲+0.72% |
| Nasdaq-100 (QQQ) | $741.10 | ▲+2.72% |
| Dow Jones (DIA) | $512.68 | ▼-0.62% |
| Russell 2000 (IWM) | $281.66 | ▼-0.86% |
| 20+ Yr Treasuries (TLT) | $79.42 | ▼-2.25% |
| Gold (GLD) | $391.69 | ▼-2.36% |
| Crude Oil (USO) | $153.09 | ▼-0.47% |
Sector Rotation
Technology led sector performance with a 2.70% gain, followed by health care at 0.88%. The remaining nine sectors declined, with utilities falling 4.23%, financials down 2.38%, and energy losing 2.66%. Sector breadth showed Information Technology's leadership was broad, with 168 of 265 stocks rising and an average gain of 2.09%. By contrast, only 6 of 61 utilities advanced, with the sector averaging a 3.21% decline. Energy saw just 26 of 99 stocks rise, averaging a 2.94% drop, while financials posted 50 advancers out of 339 and averaged a 2.30% decline.
Left: the ten SPDR sector ETFs ranked by weekly price change. Right: breadth inside each sector across the screened universe — how many of its stocks rose, and the average move.
| Sector ETF | Week |
|---|---|
| Technology (XLK) | ▲+2.70% |
| Health Care (XLV) | ▲+0.88% |
| Industrials (XLI) | ▼-0.54% |
| Materials (XLB) | ▼-0.62% |
| Consumer Disc. (XLY) | ▼-0.64% |
| Consumer Staples (XLP) | ▼-1.33% |
| Real Estate (XLRE) | ▼-2.07% |
| Financials (XLF) | ▼-2.38% |
| Energy (XLE) | ▼-2.66% |
| Utilities (XLU) | ▼-4.23% |
| Sector (stocks) | Adv / Total | Avg move |
|---|---|---|
| Information Technology | 168 / 265 | +2.09% |
| Communication | 33 / 71 | +0.03% |
| Consumer Discretionary | 99 / 215 | -0.18% |
| Industrials | 147 / 319 | -0.24% |
| Materials | 49 / 93 | -0.36% |
| Health Care | 123 / 293 | -0.40% |
| Real Estate | 30 / 107 | -1.23% |
| Consumer Staples | 27 / 87 | -1.62% |
| Financials | 50 / 339 | -2.30% |
| Energy | 26 / 99 | -2.94% |
| Utilities | 6 / 61 | -3.21% |
Top 10 Winners
Grail Inc rose 55.02% to $125.21 on a split-adjusted basis, leading the weekly gainers. Viking Therapeutics Inc gained 26.77% to $36.75 and Moderna Inc added 26.47% to $194.82; a tracked headline on September 24 noted Moderna's view of the global pharma industry. Innodata Inc rose 25.78% to $71.87 and Surgery Partners Inc gained 23.96% to $14.20 on a split-adjusted basis.
Among large-caps, Meta Platforms Inc rose 16.80% to $777.59; a tracked headline on September 24 stated Meta's $14 billion AI bet looks like it is finally paying off. Intel Corp gained 17.30% to $127.39; a tracked headline noted ASML dropped 1.8% as $400 million high-NA tools reach more fabs. Advanced Micro Devices Inc added 12.40% to $629.26 and Cadence Design Systems Inc rose 13.82% to $322.00. On the downside, Cullinan Therapeutics Inc fell 26.76% to $15.44, Alkami Technology Inc declined 25.88% to $14.18, and Gen Digital Inc dropped 20.48% to $23.07. Among large-caps, Allstate Corp fell 9.07% to $227.17, Airbnb Inc declined 8.92% to $151.39, and Intuit Inc lost 8.60% to $277.13.
Largest weekly gains among US-listed stocks with market cap above $1B and share price above $5. Context shows the week's earnings result and latest tracked headline where available.
Biggest gainers · Sep 18–Sep 24
| Symbol | Week | Context |
|---|---|---|
| GRALGrail Inc$125.21 | ▲+55.02% | —* split/data-adjusted |
| VKTXViking Therapeutics Inc$36.75 | ▲+26.77% | — |
| MRNAModerna Inc$194.82 | ▲+26.47% | Moderna's View of the Global Pharma Industry |
| INODInnodata Inc$71.87 | ▲+25.78% | — |
| SGRYSurgery Partners Inc$14.20 | ▲+23.96% | —* split/data-adjusted |
| VICRVicor Corp$276.06 | ▲+23.95% | —* split/data-adjusted |
| BANDBandwidth Inc$61.83 | ▲+23.09% | — |
| TWLOTwilio Inc$299.66 | ▲+22.89% | — |
| VCYTVeracyte Inc$48.54 | ▲+21.98% | — |
| ARHSArhaus Inc$9.47 | ▲+21.57% | — |
Top 10 Losers
Largest weekly declines on the same screen.
Biggest decliners · Sep 18–Sep 24
| Symbol | Week | Context |
|---|---|---|
| CGEMCullinan Therapeutics Inc$15.44 | ▼-26.76% | — |
| ALKTAlkami Technology Inc$14.18 | ▼-25.88% | — |
| GENGen Digital Inc$23.07 | ▼-20.48% | — |
| GSHDGoosehead Insurance Inc$43.65 | ▼-19.98% | —* split/data-adjusted |
| INNVInnovAge Holding Corp$8.84 | ▼-19.05% | — |
| AESIAtlas Energy Solutions Inc$10.99 | ▼-18.89% | — |
| ACADACADIA Pharmaceuticals Inc$22.18 | ▼-18.72% | — |
| PLNTPlanet Fitness Inc$40.72 | ▼-17.72% | — |
| CLDXCelldex Therapeutics Inc$31.48 | ▼-17.68% | — |
| MGTXMeiraGTx Holdings PLC$11.05 | ▼-16.60% | — |
Large-Cap Movers
The same ranking restricted to companies above $50B in market cap — the names most likely to sit in index funds and 401(k)s.
Large-cap gainers
- MRNAModerna Inc · $72.7B▲+26.47%
- INTCIntel Corp · $654.7B▲+17.30%
- METAMeta Platforms Inc · $1.90T▲+16.80%
- CDNSCadence Design Systems Inc · $77.3B▲+13.82%
- AMDAdvanced Micro Devices Inc · $836.6B▲+12.40%
Large-cap decliners
- ALLAllstate Corp · $64.4B▼-9.07%
- ABNBAirbnb Inc · $100.8B▼-8.92%
- INTUIntuit Inc · $78.1B▼-8.60%
- COHRCoherent Corp · $62.1B▼-8.43%
- MPCMarathon Petroleum Corp · $109.1B▼-7.99%
Earnings Movers
Thirteen screened companies reported earnings during the week, with mixed post-earnings reactions. The largest gain came from Manchester United PLC, which rose 6.35% to $20.94 despite an earnings miss with a 62.28% negative surprise. Worthington Enterprises Inc added 5.14% to $60.33 after an 8.25% earnings beat, and Thor Industries Inc gained 4.66% to $70.93 despite a 12.40% earnings miss. The week's sharpest post-earnings decline was Paychex Inc, which fell 12.53% to $101.59 after a 0.48% earnings miss. TD Synnex Corp declined 2.51% to $259.47 and MillerKnoll Inc fell 3.63% to $19.91, both despite earnings beats of 19.60% and 15.99% respectively.
13 companies in the screen reported quarterly results this week. These are the largest weekly moves among them, with the EPS surprise that accompanied them.
Biggest gains after reporting
| Symbol | Act / Est | Surprise | Week |
|---|---|---|---|
| MANUManchester United PLC | $-0.17$-0.10 | -62.3% | ▲+6.35% |
| WORWorthington Enterprises, Inc | $0.82$0.76 | +8.3% | ▲+5.14% |
| THOThor Industries Inc | $0.78$0.89 | -12.4% | ▲+4.66% |
| FULH.B. Fuller Company | $1.52$1.48 | +2.8% | ▲+1.19% |
| KBHKB Home | $1.05$0.90 | +16.4% | ▲+1.12% |
Biggest declines after reporting
| Symbol | Act / Est | Surprise | Week |
|---|---|---|---|
| PAYXPaychex Inc | $1.34$1.35 | -0.5% | ▼-12.53% |
| ANABAnaptysBio Inc | $5.11$0.00 | n/m | ▼-6.34% |
| MLKNMillerKnoll Inc | $0.42$0.36 | +16.0% | ▼-3.63% |
| SNXTD Synnex Corp | $5.68$4.75 | +19.6% | ▼-2.51% |
| DRIDarden Restaurants Inc | $2.05$2.08 | -1.2% | ▼-0.97% |
Methodology & Disclaimer
Data. All figures come from Money365.Market's own daily price, earnings and analyst-recommendation records, captured at each US close. Returns are price returns from the Sep 18 close to the Sep 24 close; dividends are excluded.
Screen. 1,951 US-listed common stocks with market capitalization of at least $1B and a closing price of at least $5, with prices on at least three of the week's 4 trading days. ETFs and funds are excluded from the stock rankings.
Adjustments. Weekly moves are compounded from daily changes and cross-checked against closing prices; where the two disagree (stock splits, data corrections) the smaller move is used and the row is marked with an asterisk. This week: CNXC, GRAL, GSHD, MAZE, OMER, SGRY, TNGX, VICR.
Narrative. The short prose sections were drafted by an AI model from the verified data above only, then checked automatically for number and ticker traceability, editorial tone and FCA financial-promotion wording before publication.
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